How SMART IRB Works
For Investigators & Study Teams
Reduces hurdles for multisite collaborations Supports small and large studies, regardless of funding. Helps to obtain trial results faster.
Single IRB Review
SMART IRB helps streamline human subjects research, while ensuring robust protections for study participants. SMART IRB can be used for a range of research, from large, complex clinical trials to two-site collaborations. Clinical investigators can obtain trial results faster and, ultimately, speed development of new diagnostics, treatments, and preventative measures for patients.
How it Works
Multisite Study
The Overall Principal Investigator (PI) of a multisite study works with the Points of Contact (POCs) for each participating institution involved in the study to determine an appropriate reliance arrangement.
Identify & Determine
Together PI and POCs will identify a Reviewing IRB and determine which institutions will rely upon that IRB for the review and oversight of the research.
Additional details on these processes are available in the SMART IRB SOPs on “Establishing Reviewing IRBs and Relying Institutions” and “Initial Review Submission and Review Process.” See the Resources page.
Your Responsibilities
Whether you are the Overall PI or a collaborating Site Investigator, if your study uses the SMART IRB Agreement, you assume specific responsibilities, in addition to your regulatory obligations as an investigator. For more information, see the roles and responsibilities described in the SMART IRB Standard Operating Procedures (SOPs).
Join SMART IRB
Join the platform to harmonize and streamline the IRB review process for multisite studies, while ensuring a high level of protection for research participants.
